Laser Diffraction · Analysis Method

Particle Size Measurement Technology

Laser Particle
Size Analysis

ISO 13320 Mie & Fraunhofer 0.02–3,500 µm Wet & Dry Dispersion DLOI Wide-Angle Optics

Laser diffraction measures the angular intensity distribution of light scattered by particles and converts it into a particle size distribution. The full range from 0.02 µm to 3,500 µm is covered in a single pass. Measurement time is under 60 seconds, with results verifiable against ISO 13320.

0.02 µm
Lower size limit
165°
Maximum scatter angle
<60 sec
Typical measurement time
Laser Diffraction Particle Size Analysis
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0.02–3,500 µm
Total measurement range (nano to coarse fraction)
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0.016°–165°
DLOI wide-angle scatter coverage
ISO 13320
International laser diffraction standard compliance
<60 sec
Typical measurement time, <0.5% CV repeatability
DLOI Wide-Angle Optical System

DLOI: 0.016°–165°
Wide-Angle Coverage

Most standard laser diffraction systems operate between 0° and 90°. Small particles scatter light at angles beyond this range, which introduces measurement error. The DLOI (Dual Lens Optical Instrument) system covers the full angular range from 0.016° to 165° in a single measurement — without lens changes.

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Wide Angular Range, Single Measurement
The photodetector array spanning 0.016° to 165° collects scatter signals from both fine and coarse particles simultaneously.
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No Manual Lens Swapping
Switching between size ranges requires no lens removal or installation. This eliminates operator-induced error and reduces measurement time.
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Nanometer-Level Sensitivity
The lower detection limit of 0.02 µm serves colloidal dispersions and fine API powders that require wide-angle optical coverage.
Laser Diffraction Scatter Pattern and Calculation Models

Fraunhofer or Mie?
Sample-specific selection

Two mathematical models describe how light interacts with particles in laser diffraction. Selecting the correct model is critical for reliable results.

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Fraunhofer Approximation
Assumes particles deflect light by diffraction only. Reliable for opaque particles above 1 µm. No refractive index input is required, making it fast and straightforward.
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Mie Theory
Accounts for light transmission through the particle and the refractive index. Preferred for particles below 1 µm and for transparent materials where Fraunhofer assumptions break down.
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Instant Results, Full Distribution
Each measurement reports D10, D50, D90 values along with frequency and cumulative distribution curves in real time.

Industries Using
Laser Diffraction

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Pharmaceutical
API and excipient size control, inhalation products, USP <429> and 21 CFR Part 11 compliant manufacturing processes.
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Ceramics & Glass
Raw material particle size and distribution uniformity before sintering; directly determines mechanical properties of the final product.
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Paints, Pigments & Coatings
Pigment agglomerate detection, opacity and color strength optimization, serial dispersion stability control.
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Food & Agrochemicals
Emulsion stability, powdered food distribution, pesticide formulation repeatability.
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Construction Materials
Particle size distribution of cement, lime and concrete admixtures for process and quality control.
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Battery Materials
Particle size and morphology optimization of cathode and anode active material powders; influences energy density.
Minerals & Mining
Grinding process control, coarse fraction monitoring, size optimization for flotation efficiency.
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Research & Development
Material characterization, nano-dispersion studies, new formulation development workflows.

Bettersize Series for
Laser Particle Size Analysis

All Bettersize instruments use the DLOI wide-angle optical system. Model selection is based on measurement range, dispersion requirements, and application.

About Laser Diffraction

A laser beam interacts with particles in the sample and scatters. Small particles scatter light at wide angles; large particles scatter at narrow angles. Detectors measure this angular intensity distribution. The software then converts the scatter pattern into a particle size distribution using either Mie theory or the Fraunhofer approximation. A typical measurement completes in under 60 seconds.

Modern laser diffraction instruments measure from 0.02 µm to 3,500 µm. The lower limit depends on the optical system — the DLOI wide-angle optic reaches 0.02 µm. The upper limit is determined by the dispersion unit capacity. A single instrument covers both nano-scale particles and coarse powders.

The Fraunhofer approximation is sufficient for opaque particles above 1 µm and requires no refractive index input. Mie theory is preferred for particles below 1 µm or for transparent materials; it requires the material's real and imaginary refractive indices for accurate calculation. Most modern software supports both models.

Wet dispersion is suited for powders sensitive to solvation, pharmaceutical APIs, and fine particles — the liquid medium separates agglomerates and reveals true primary particle size. Dry dispersion is preferred for solvent-sensitive materials, high-throughput routine analysis, and samples that are stable in air. Some instruments support both modes on the same platform.

ISO 13320 is the international method standard for particle size analysis by laser diffraction. Compliance means the instrument meets defined criteria for measurement principle, validation procedures, and reporting requirements. This standard is widely referenced in pharmaceutical, food, and chemical industry specifications.

Key decision points: if particle shape also needs to be measured, the Bettersizer 2600 Plus or S3 Plus includes the PIC-1 imaging module. If size distribution alone is sufficient, the 2600E or ST is more cost-effective. If the 0.1–1,000 µm range covers your needs, the ST is adequate; for wider ranges, the 2600 series is the better fit. Contact us for a demo with your own sample material.

Request a Demo
with Your Sample

Contact our team for laser particle size analysis instruments, application support, or sample measurement. Bettersize Authorized Distributor in Türkiye, with over 25 years of experience.

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+90 (216) 577 52 96Phone
info@ankaanalitik.com.trEmail
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WhatsApp+90 549 252 76 46
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Kadıköy, Istanbul19 Mayıs Mah. Sumer Sok. Sumko Sitesi A7 Blok No:3CL
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